peptide linkage

A review with 47 references on the strategy of disulfide bond formation in peptide synthesis and the methods for analyzing disulfide linkage patterns in peptides is presented.

综述了目前多肽合成领域构建2～3个二硫键的策略和对二硫键排列方式给予定位的方法。

Reduced glutathione, abbreviated as GSH, is a tri-peptide which is made up of glutamic acid, cysteine and glycine. Among these amino acids, aminoglutaminic acid' gamma carboxyl group and cysteine join into action to form peptide linkage.

还原型谷胱甘肽（L-Glutathione）简称为GSH，是由谷氨酸、半胱氨酸和甘氨酸构成的三肽，其中谷氨酸是以γ-羧基与半胱氨酸形成肽键。

Formation of disulfide bond correctly and high efficiently is the key of synthesis of multiple disulfide boned-containing peptide. This article reviewes the strategy and optimization of disulfide bond formation and the method for analyzing disulfide linkage patterns in peptide.

二硫键的正确配对是富含二硫键多肽合成的关键，本文综述了含两对二硫键以上的多肽二硫键的形成策略、优化方法、以及二硫键配对方式的测定方法。